Molecular Details
DICL_CP_0306972
- zinc(2+)
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0306972
PubChem CID
Molecular Formula
Zn+2 Molecular Weight
65.39 g/mol
Synonyms/Alias
[zinc ion; zinc(2+); Zinc cation; 23713-49-7; Zinc; ion (Zn2+); zinc(II); Zn2+; Velmanase Alfa; Topostin B; 9025-42-7; Zinc(2+)ions; Zinc ion(2+); Zinc 2+; Lamazym; Rhlaman; Velmanase Alfa [INN]; zinc...
InChI Key
PTFCDOFLOPIGGS-UHFFFAOYSA-N
InChI
InChI=1S/Zn/q+2
IUPAC Name
zinc(2+)
CAS Number
1314-13-2
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
1 0 0 0 0 0 0 0 0 0999 V2000
0.0000 0.0000 0.0000 Zn 0 0 0 0 0 15 0 0 0 0 0 0
M CHG 1 1 2
M END
$$$$
Experimental Data
Activity Data
Target Ion Channel
epithelial calcium channel (ECaC1)
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 3800 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
Extracellular solution pH 7.4/Intracellular solution pH 7.2
Holding Potential
−100 mV mV
Temperature
20−22 °C
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
1
Rotatable Bonds
0
logP
-0.0025
Complexity
2.5
TPSA (Ų)
0
H-Bond Donors
0
H-Bond Acceptors
0
Ring Count
0